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Table of Contents > Drug > Ofatumumab Print

Ofatumumab

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: ArzerraT
    • Pharmacologic Category: Antineoplastic Agent, Monoclonal Antibody;Monoclonal Antibody

    Uses
    • It is used to treat leukemia.
    • Ofatumumab harms cancer cells causing their death.

    Dosing

    How to take

    • It is given as a shot into a vein over a period of time.
    • Acetaminophen, diphenhydramine, and a corticosteroid may be given before this drug to lower fever and chills.

    Missed Dose

    • Call your doctor to find out what to do.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Avoid

    • If you have an allergy to ofatumumab or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.

    Precautions

    • Hepatitis B testing may be done. A hepatitis B infection may get worse during care.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of a very bad infection or make the vaccine not work as well.
    • Very bad infections have been reported with use of this drug. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
    • Use birth control that you can trust to stop pregnancy while taking this drug and for up to 12 months after this drug.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
    • Feeling tired or weak.
    • Chance of getting an infection. Avoid people with infections, colds, or flu.
    • Loose stools.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Cough.
    • Low white blood cell count or low platelet count.
    • Fever, chills, itching, hives, chest pain or pressure, or shortness of breath when drug is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5F (38C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Change in thinking clearly and with logic.
    • Very bad dizziness or passing out.
    • Big change in balance.
    • Trouble breathing.
    • Trouble speaking.
    • Feeling very tired or weak.
    • Very upset stomach or throwing up.
    • Very bad belly pain.
    • Yellow skin or eyes.
    • Very loose stools.
    • Any bruising or bleeding.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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