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Table of Contents > Drug > Abacavir and Lamivudine Print

Abacavir and Lamivudine

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Epzicom®
    • Brand Names: Canada: KivexaT
    • Mexican Brand Names: Kivexa
    • Pharmacologic Category: Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)

    Uses
    • It is used to treat HIV infection.
    • Abacavir and lamivudine works to harm the virus and fight the infection.

    Dosing

    How to take

    • In HIV care, this drug is most often taken with 2 other drugs.
    • To gain the most benefit, do not miss doses.
    • Use as you have been told, even if you are feeling better.
    • Take with or without food. Take with food if it causes an upset stomach.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose, brand, or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Unsafe allergic effects may happen. Tell your doctor about any fever, rash, feeling tired, upset stomach, throwing up, loose stools, belly pain, flu-like signs, sore throat, cough, or trouble breathing. Do not restart this drug if you have had an allergic reaction.
    • This drug may cause liver problems and a change in acid levels in the blood. Closely read the part in this leaflet which lists when to call your doctor. Pregnancy, obesity, and/or longer therapy may raise this chance.
    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.
    • Read the warning card and carry it with you at all times. It tells the signs to watch for in case an allergy happens.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to abacavir, lamivudine, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have liver disease.

    Precautions

    • If this drug is stopped because you have an allergy to it, do not restart it. It may not be safe to restart this drug.
    • If this drug is stopped for any other reason, do not restart it without talking to the doctor. It could be very risky to restart on your own.
    • If this drug changes for HIV infection, make sure to ask your doctor about hepatitis B care.
    • Do not run out of this drug.
    • Wear disease medical alert ID (identification).
    • Use care if you have risks for heart disease (high blood pressure, high cholesterol, overweight, high blood sugar (diabetes), cigarette smoking, man older than 40 years of age, other family members with early heart disease, woman after change of life). Talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Avoid beer, wine, or mixed drinks.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • To protect from diseases caused by having sex, use a latex condom.
    • Use birth control that you can trust to stop pregnancy while taking this drug.
    • Do not breast-feed if you have HIV disease and live in the U.S.

    Side Effects

    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Not hungry.
    • Irritated pancreas may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Allergic reaction (fever, rash, feeling tired, upset stomach, throwing up, loose stools, belly pain, sore throat, cough, trouble breathing, or flu-like signs). Stop this drug and talk with your doctor right away!
    • Trouble breathing.
    • Very bad dizziness or passing out.
    • A fast heartbeat.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Very loose stools.
    • Very bad muscle pain or weakness.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • Feeling cold.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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