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Table of Contents > Drug > Adalimumab Print

Adalimumab

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Humira®;Humira® Pen
    • Brand Names: Canada: Humira®
    • Mexican Brand Names: Humira
    • Pharmacologic Category: Antirheumatic, Disease Modifying;Gastrointestinal Agent, Miscellaneous;Monoclonal Antibody;Tumor Necrosis Factor (TNF) Blocking Agent

    Uses
    • It is used to stop more problems in patients with moderate to very bad rheumatoid arthritis.
    • It is used to treat psoriatic arthritis.
    • It is used to treat Crohn's disease.
    • It is used to treat ankylosing spondylitis.
    • It is used to treat psoriasis.
    • It is an arthritis-changing drug. It lowers swelling and helps lower signs and protect joints from more harm.
    • It helps swelling.
    • It lowers the body's harmful response to diseases of the immune system.
    • It helps lower GI (gastrointestinal) swelling and other signs.

    Dosing

    How to take

    • You will need a TB (tuberculosis) test before starting this drug.
    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Wash your hands before and after use.
    • Throw syringe away after use. Do not use more than one time.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store in a refrigerator. Do not freeze.
    • Protect from light.

    Safety



    Warnings

    • TB (tuberculosis) has been seen in patients started on adalimumab. These patients were exposed to TB in the past, but never had the infection. You will be tested to see if you have been exposed to TB.
    • This drug may add to your chance of getting lymphoma or other cancers.
    • Very bad infections have happen in patients who take these types of drugs. Talk with the doctor.
    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to adalimumab or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.
    • If you have a latex allergy, talk with your doctor.

    Precautions

    • Hepatitis B testing may be done. A hepatitis B infection may get worse during care.
    • Long-term use may raise your chance of cancer.
    • Very bad infections have been reported with use of this drug. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of a very bad infection or make the vaccine not work as well.
    • If you have heart disease, talk with your doctor.
    • If you have MS (multiple sclerosis) or other nerve disease, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Chance of getting an infection. Avoid people with infections, colds, or flu.
    • Headache.
    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
    • Irritation where the shot is given.

    Monitoring

    • Change in the health problem being treated. Is it better, worse, or about the same?
    • Follow up with the doctor.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Trouble breathing.
    • Swelling in your legs or belly.
    • Chest pain or pressure.
    • Very bad headache.
    • Not able to eat.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Feeling very tired or weak.
    • Very bad back pain.
    • Numbness or tingling in your hands or feet.
    • Any bruising or bleeding.
    • Dark urine or yellow skin or eyes.
    • Night sweats.
    • A big weight loss.
    • Fever that does not go away.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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