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Table of Contents > Drug > Amoxicillin and Clavulanate Print

Amoxicillin and Clavulanate

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Amoclan;Augmentin ES-600® [DSC];Augmentin XR®;Augmentin®
    • Brand Names: Canada: Amoxi-Clav;Apo-Amoxi-Clav®;Clavulin®;Novo-Clavamoxin;ratio-Aclavulanate
    • Mexican Brand Names: Acarbixin;Amobay Cl;Amoxiclav;Amoxiclav-BID;Augmentin;Clamoxin;Clavant;Clavipen;Clavucyd;Clavulin;Clavuser;Gimaclav;Moxlin;Riclasip;Servamox;Sinufin
    • Pharmacologic Category: Antibiotic, Penicillin

    Uses
    • It is used to treat bacterial infections.
    • Amoxicillin works to harm the bacteria and fight the infection.
    • Clavulanate protects amoxicillin from being wiped out by some types of bacteria.

    Dosing

    How to take

    • To gain the most benefit, do not miss doses.
    • Use as you have been told, even if you are feeling better.
    • Take with or without food. Take with food if it causes an upset stomach.
    • Chewable tablet: Chew or crush well. Mix crushed tablet with food. Do not swallow it whole.
    • There is a liquid (suspension) if you cannot swallow pills. Shake well before use.
    • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
    • Scored long-acting product: Do not chew or crush.
    • Unscored long-acting product: Swallow whole. Do not chew, break, or crush.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store tablets at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • Store liquid (suspension) in a refrigerator. Do not freeze. Throw away any part not used after 10 days.

    Safety



    Avoid

    • If you have an allergy to amoxicillin, clavulanate potassium, any penicillin, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If this drug caused liver problems before.
    • Augmentin XRT: If you have very bad kidney disease or are on dialysis.

    Precautions

    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have PKU, talk with your doctor. Some products have phenylalanine.
    • If you are taking a blood thinner, have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Avoid beer, wine, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools. Yogurt or probiotics may help. You may get these products at health food stores or in some pharmacies.
    • For women, vaginal yeast infection. Report itching or discharge.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very upset stomach or throwing up.
    • Very loose stools, even after drug is stopped.
    • Any bruising or bleeding.
    • Dark urine or yellow skin or eyes.
    • Not able to eat.
    • Feeling very tired or weak.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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