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Table of Contents > Drug > Amphotericin B (Liposomal) Print

Amphotericin B (Liposomal)

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: AmBisome®
    • Brand Names: Canada: AmBisome®
    • Pharmacologic Category: Antifungal Agent, Parenteral

    Uses
    • It is used to stop or treat yeast infections.
    • Amphotericin works to harm the yeast and fight the infection.

    Dosing

    How to take

    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Call your doctor for an office visit.

    Storage

    • Store at room temperature.
    • Protect from light.

    Safety



    Warnings

    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to amphotericin or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.

    Precautions

    • If you have kidney disease, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • You may need extra potassium or magnesium. Talk with your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. You may be given drugs before this shot to avoid these signs.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Low potassium levels. Signs include feeling tired, weak, numbness, or tingling; muscle cramps; hard stools (constipation); throwing up; or a fast heartbeat.
    • Low blood pressure.
    • Belly pain.
    • Anemia, low white blood cell count, and low platelet count may rarely happen.
    • Cough.
    • Change in balance.
    • Flushing.
    • Kidney function that gets worse.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Trouble breathing.
    • A fast heartbeat.
    • Big change in balance.
    • A big weight gain.
    • Very bad swelling.
    • Not able to pass urine.
    • Cloudy or pink-red urine.
    • Dark urine or yellow skin or eyes.
    • Very bad belly pain.
    • Very loose stools.
    • Not able to eat.
    • Feeling very tired or weak.
    • Very bad muscle pain or weakness.
    • Numbness or tingling in your hands or feet.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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