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Table of Contents > Drug > Zoledronic Acid Print

Zoledronic Acid

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Reclast®;Zometa®
    • Brand Names: Canada: Aclasta®;Zometa®
    • Mexican Brand Names: Zometa
    • Pharmacologic Category: Antidote;Bisphosphonate Derivative

    Uses
    • It is used to treat high calcium levels.
    • It is used when treating some cancers.
    • It is used to treat Paget's disease.
    • It is used to put off or treat soft, brittle bones (osteoporosis).
    • Zoledronic acid lowers bone loss.

    Dosing

    How to take

    • It is given as a shot into a vein over a period of time.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • Recast®: Drink at least 2 glasses of liquids a few hours before you get this drug.
    • Take calcium and vitamin D as you were told by your doctor.
    • Acetaminophen may be given to lower fever and chills.

    Missed Dose

    • Call your doctor for an office visit.

    Storage

    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • Please read the medication guide.

    Avoid

    • If you have an allergy to zoledronic acid or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • Reclast®: If you have low calcium levels or very bad kidney disease.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • If you are dehydrated, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have malabsorption syndrome or have had part of your bowel taken out, talk with your doctor.
    • If you have had thyroid or parathyroid surgery, talk with your doctor.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Have your blood work checked often. Talk with your doctor.
    • Have a bone density test. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Have a dental exam before starting this drug.
    • Take good care of your teeth. See a dentist often.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Irritation where the shot is given.
    • High or low blood pressure.
    • Feeling tired or weak.
    • Belly pain.
    • Loose stools.
    • Swelling in the arms or legs.
    • Headache.
    • Fever.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Low calcium levels.
    • Anemia.
    • Bone, joint, or muscle pain may rarely happen.
    • A broken leg may rarely happen.
    • Harm to the jaw bone may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very upset stomach or throwing up.
    • Very loose stools.
    • Very bad jaw pain.
    • Very bad bone, joint, or muscle pain.
    • Very bad groin or thigh pain.
    • Numbness or tingling in your mouth.
    • Numbness or tingling in your hands or feet.
    • Twitching.
    • Not able to pass urine.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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